Degradation of [3H]β-endorphin in rat plasma is increased with chronic stress
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منابع مشابه
Degradation of [3H]beta-endorphin in rat plasma is increased with chronic stress.
With a number of acute stressors beta-endorphin is released into plasma. It is unclear if beta-endorphin is converted into any other biologically active products, nor is it clear if the rate or pathways of degradation are changed during chronic stress. To explore these issues, we incubated [3H]beta-endorphin h labeled in positions 1 and 27 with plasma from normal and chronically footshocked rat...
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The activation of the hypothalamic pituitary adrenal axis by stress is well-known. Using inescapable intermittent footshock as a stressor in rats, we have previously demonstrated a rise in circulating plasma Beta-endorphin/Beta-LPH which parallels the rise in plasma ACTH, the primary POMC derived peptides released by anterior lobe. In addition, the rise in ACTH is accompanied by approximately a...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 1989
ISSN: 0014-2999
DOI: 10.1016/0014-2999(89)90583-9